Four of the medications have already been discontinued: Tilade, Intal, Azmacort and Alupent; and two of the remaining three have a small market share: Aerobid and MaxAir. Combivent is used by patients with chronic obstructive pulmonary disease (COPD) and by some patients who have both COPD and asthma.
The phase-out dates for each of these can be read here: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm208302.htm. [^]
We expect that an Aerobid HFA replacement will be approved prior to its phase-out. We expect the same for Combivent.
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